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Editor-in-Chief eMediNexus – Dr KK Aggarwal
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6th May 2018
Administer oxygen therapy with caution
Supplementation of high levels of oxygen increases mortality risk

Dr KK Aggarwal, Recipient of Padma Shri

Prompt oxygen supplementation has become a routine practice in critically ill patients primarily to correct tissue hypoxia and maintain adequate oxygenation due to arterial hypoxemia in acute illnesses such as respiratory distress, cardiac arrest, myocardial infarction. Oxygen therapy in these situations is life saving (J Intern Med. 2013;274(6):505-28). Tissue hypoxia occurs within 4 minutes of failure of any of these systems because the oxygen reserves in tissue and lung are relatively small (BMJ. 1998;317(7161):798-801).

Recently, however, focus has been on the harmful effects of high levels of oxygen or ‘oxygen toxicity’ because of the vasoconstrictor effect of hyperoxemia and the risk of significant blood flow reduction to the at-risk tissue, especially on normal, nondiseased vasculature (J Intern Med. 2013;274(6):505-28)..... read more

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Top News

ICMR launches May Measurement Month 2018 to raise awareness on hypertension

The Indian Council of Medical Research (ICMR) has launched a campaign to raise awareness on hypertension. Co-organized with the Public Health Foundation of India, International Society of Hypertension and other partner institutions, the campaign called “May Measurement Month 2018” .... read more

Morning Medtalks

Morning Medtalks with Dr KK Aggarwal 6th May

Public Health: A Phase 2 clinical trial of an investigational universal influenza vaccine intended to protect against multiple strains of the virus has begun in the United States. The trial is testing an experimental vaccine called M-001 for safety and its ability to produce potentially broad protective immune responses, both on its own and when followed by a standard, licensed seasonal influenza vaccine.... read more

Practice Updates

First FDA-approved treatment for patients with BRAF-positive anaplastic thyroid cancer

The US Food and Drug Administration (FDA) has approved Tafinlar (dabrafenib) and Mekinist (trametinib), administered together, for the treatment of anaplastic thyroid cancer (ATC) that cannot be removed by surgery or has spread to other parts of the body.... read more

Andexanet Alfa approved for rapid NOAC reversal

The FDA has granted approval to andexanet alfa (Andexxa), the first antidote indicated for the rapid reversal of anticoagulation due to major bleeding in patients treated with Factor Xa inhibitors rivaroxaban.... read more

ACC/HRS/NASCI/SCAI/SCCT expert consensus statement on ionizing radiation in CV imaging

An expert consensus document on optimal use of ionizing radiation in cardiovascular imaging has been published online May 2, 2018 in the Journal of the American College of Cardiology. The document developed by the American College of Cardiology (ACC) in collaboration... read more

All older men to be screened for osteoporosis

A new study presented May 3, 2018 at the American Geriatrics Society (AGS) 2018 Annual Scientific Meeting in Orlando, Florida has recommended that all men aged 85 years and older should be screened for osteoporosis,... read more

Infants exposed to hepatitis C virus during pregnancy should be screened for infection after delivery

A study published online May 2, 2018 in the journal Pediatrics says that infants exposed to hepatitis C virus during pregnancy often are not screened for infection after delivery. Based on their findings, where only 96 of the 363 infants were screened for hepatitis C virus,.... read more

Study shows increased risk of hearing loss with reduced kidney function

Reduced kidney function as estimated using cystatin C, but not cystatin C alone, was associated with hearing impairment, suggesting that some age-related HI may occur in conjunction with or as the result of reduced kidney function..... read more

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Lifestyle Updates
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Inspirational Story 2: The Good you do, comes back to you
Sleep can affect the incidence of chronic kidney disease
Only about 10% to 15% of kidney patients get requisite treatment
New Delhi, 05 May 2018: Sleep duration is extremely vital for kidney disease patients, a recent research has indicated. It can influence the health-related quality of life (HRQOL) experienced by individuals with chronic kidney disease (CKD).Sleep of adequate quantity and quality is essential for homeostatic regulation, and excess sleep is associated with metabolic diseases such as obesity, diabetes, and hypertension, all of which are risk factors of CKD.

Of all the patients who develop end stage kidney failure in India, only 10% to 15% get proper treatment. About 6000 undergo kidney transplant, 60,000 undergo hemodialysis, and another 6000 prefer to take peritoneal dialysis in a year.

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